منابع مشابه
Quantized ionic conductance in nanopores.
Ionic transport in nanopores is a fundamentally and technologically important problem in view of its occurrence in biological processes and its impact on novel DNA sequencing applications. Using molecular dynamics simulations we show that ion transport may exhibit strong nonlinearities as a function of the pore radius reminiscent of the conductance quantization steps as a function of the transv...
متن کاملDehydration and ionic conductance quantization in nanopores.
There has been tremendous experimental progress in the last decade in identifying the structure and function of biological pores (ion channels) and fabricating synthetic pores. Despite this progress, many questions still remain about the mechanisms and universal features of ionic transport in these systems. In this paper, we examine the use of nanopores to probe ion transport and to construct f...
متن کاملPink noise of ionic conductance through single artificial nanopores revisited.
We report voltage-clamp measurements through single conical nanopore obtained by chemical etching of a single ion track in polyimide film. Special attention is paid to the pink noise of the ionic current (i.e., 1/f noise) measured with different filling liquids. The relative pink-noise amplitude is almost independent of concentration and pH for KCl solutions, but varies strongly using ionic liq...
متن کاملIonic memcapacitive effects in nanopores.
Using molecular dynamics simulations, we show that, when subject to a periodic external electric field, a nanopore in ionic solution acts as a capacitor with memory (memcapacitor) at various frequencies and strengths of the electric field. Most importantly, the hysteresis loop of this memcapacitor shows both negative and diverging capacitance as a function of the voltage. The origin of this eff...
متن کاملActively Controlled Ionic Current Gating in Nanopores
A conical nanopore was developed that allowed the ionic current to be gated by external application of electrical potential. A numerical model of the pore was created in COMSOL to elucidate the mechanism of action in this pore. The model is composed of a conical nanopore geometry with a gold-plated Si3N4 structure and a complete Gouy-Chapman-Stern electrical double layer. The Poisson, NernstPla...
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ژورنال
عنوان ژورنال: Biophysical Journal
سال: 2009
ISSN: 0006-3495
DOI: 10.1016/j.bpj.2008.12.3853